Loss of Touch Sensation
As the disease progresses, the bacteria continue to attack and permanently damage the nerves, which causes patients to experience a decreased or lost sense of touch, then pain and eventually deep pressure. This is particularly dangerous because injuries to extremities may go unnoticed or untreated.
Painless Ulcers and Skin Lesions
Flat, pale areas of skin develop on leprosy patients, called lesions. These skin lesions have a lighter pigmentation than normal skin color, as well as decreased sensitivity to touch, heat or pain. They may not heal after several weeks or months and may accompany growths on the skin and thick, stiff, or dry skin. Ulcers may develop on the body, including on the soles of the feet.
Eye Damage
Leprosy can damage facial nerves, causing the eyelid muscles to stop working properly. Because the eyes no longer are protected by the blinking mechanism, and because they can be so easily damaged, this can eventually lead to blindness.
Muscle Weakness
Muscle weakness or paralysis may occur as the disease progresses, especially in the hands and feet and may spread to the arms and legs. This muscle paralysis can cause clawed fingers and foot drop, both characteristic of leprosy patients.