Acetaminophen is the most common OTC medication used for fever and minor aches and pain. It is especially important to administer this to people who cannot take anti-inflammatories like NSAIDS or aspirin.

The adult dosage is four grams a day to prevent liver toxicity. Anyone suffering from cirrhosis or hepatitis should avoid acetaminophen. Dosages for children and teens are based on weight so be careful about dosing amount. Tylenol and Panadol contains acetaminophen.

Most NSAIDs are available over-the-counter to treat fever, inflammation and pain. The NSAID ibuprofen is often prescribed for minor orthopedic injuries because it lowers both pain and inflammation. This med is also used for fever in all age groups.

With overuse, there is the potential for bleeding from stomach or bowels. It is also not recommended for individuals on blood thinners. Examples of NSAIDs are Motrin and Advil. 

Aspirin or salicylic acid has been used for generations as a pain, anti-inflammatory and fever medication. Aspirin is the first line of defense against sudden heart attacks and strokes because of its anti-clotting properties.

Because of aspirin’s side effects, physicians may recommend other pain reducers like ibuprofen or acetaminophen. Also, don’t give aspirin to anyone under the age of 14. There is the risk of contracting Reye’s syndrome which causes fatal brain swelling in infants and children.

Individuals with stomach bleeding problems or stomach ulcers should not take aspirin. Those on blood thinners, of course, have to be careful combining the two. Examples of OTC aspirin are Bayer, St. Joseph’s and Anacin.